BDBM50103242 CHEMBL316894::Naphthalene trisulfonate (NTS)::naphthalene-1,3,6-trisulfonate(3-)::trisodium naphthalene-1,3,6-trisulfonate

SMILES c1cc2c(cc1S(=O)(=O)[O-])cc(cc2S(=O)(=O)[O-])S(=O)(=O)[O-]

InChI Key InChIKey=ZPBSAMLXSQCSOX-UHFFFAOYSA-K

Data  1 KI  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103242   

TargetDual specificity protein phosphatase 5 [180-384](Human)
Texas Wesleyan University

LigandPNGBDBM50103242(naphthalene-1,3,6-trisulfonate(3-) | CHEMBL316894 ...)
Affinity DataIC50: 6.40E+6nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMed
TargetFibroblast growth factor 1(Human)
Progen Industries

Curated by ChEMBL
LigandPNGBDBM50103242(naphthalene-1,3,6-trisulfonate(3-) | CHEMBL316894 ...)
Affinity DataKd:  4.74E+5nMAssay Description:Dissociation constant for Fibroblast growth factor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor 2(Human)
Progen Industries

Curated by ChEMBL
LigandPNGBDBM50103242(naphthalene-1,3,6-trisulfonate(3-) | CHEMBL316894 ...)
Affinity DataKd:  2.23E+5nMAssay Description:Dissociation constant for Fibroblast growth factor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103242(naphthalene-1,3,6-trisulfonate(3-) | CHEMBL316894 ...)
Affinity DataKi: >4.00E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed