BDBM50099618 CHEMBL1232635

SMILES c1cc(ccc1C(c2ccc(cc2)F)N3CCN(CC3)C(=O)n4cncn4)F

InChI Key InChIKey=UIOVHJYJUUSVIG-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50099618   

TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 282nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.851nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.219nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.219nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed