BDBM50098068 1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID::1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyrazole-4-carboxylic acid::CHEMBL169526

SMILES CC(C)(C)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O

InChI Key InChIKey=AETHRPHBGJAIBT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098068   

TargetXanthine dehydrogenase/oxidase(Bovine)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 5.80nMAssay Description:In vitro inhibitory concentration against Xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of bovine milk xanthine-oxygen reductase using xanthine as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid production using xanthine as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Guangzhou General Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Guangzhou General Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed