BDBM50097860 CHEMBL3589671

SMILES c1cc2c3c(c4cc(ccc4nc3C(=O)O)I)[nH]c2c(c1)Cl

InChI Key InChIKey=WGBRJADREQKUMW-UHFFFAOYSA-N

Data  11 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50097860   

TargetDual specificity protein kinase CLK1(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant CDK9 expressed in insect cells using CDK7/9 tide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DYRK3 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK2 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097860(CHEMBL3589671)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)