BDBM50093434 CHEMBL3586670

SMILES CC(=O)Nc1nc2c(s1)CN(CC2)c3cncc(n3)OC

InChI Key InChIKey=YGHXBCAMJWBJDS-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093434   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50093434(CHEMBL3586670)Copy SMILESCopy InChI

Affinity DataKi:  0.0170nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using [33P]ATP and PIP2 incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/13/2016
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL