BDBM50081594 6-Phenyl-5,6,7,8-tetrahydro-pteridine-2,4-diamine::6-phenyl-5,6,7,8-tetrahydropteridine-2,4-diamine::CHEMBL327287

SMILES c1ccc(cc1)[C@@H]2CNc3c(c(nc(n3)N)N)N2

InChI Key InChIKey=VEKRIXRQADJFAG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081594   

TargetNitric oxide synthase, endothelial(Pig)
Julius-Maximilians University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50081594(6-phenyl-5,6,7,8-tetrahydropteridine-2,4-diamine |...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against Nitric oxide synthase (derived from porcine brain cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50081594(6-phenyl-5,6,7,8-tetrahydropteridine-2,4-diamine |...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed