BDBM50080821 (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol::8R-hydroxylobelane::CHEMBL125511

SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1

InChI Key InChIKey=MUSFCRGEWKAWEE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080821   

TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080821((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080821((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of [3H]MLA binding to alpha-7 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080821((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  1.88E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080821((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  1.98E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080821((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of [3H]NIC binding to alpha-4-beta-2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed