BDBM50080814 (S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol::10S-hydroxylobelane::CHEMBL122317

SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1

InChI Key InChIKey=MUSFCRGEWKAWEE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080814   

TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080814((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080814((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H]NIC binding to alpha-4-beta-2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080814((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  3.09E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080814((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  4.27E+3nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080814((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)
Affinity DataKi:  3.93E+4nMAssay Description:Inhibition of [3H]MLA binding to alpha-7 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed