BDBM50079565 CHEMBL3417489

SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1

InChI Key InChIKey=AVMUXOWCRXLJPW-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50079565   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EPHA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of recombinant human His-tagged c-Met cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression system using poly (Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50079565(CHEMBL3417489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full length HDAC1 expressed in baculovirus infected Sf9 insect cells using biotinylated lysine 9 acetylated histone H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed