BDBM50074933 2-biphenyl-4-yl-propionic acid::CHEMBL317434::alpha-Methyl-4-biphenyl-acetic acid

SMILES CC(C(O)=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=JALUUBQFLPUJMY-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50074933   

TargetProstaglandin G/H synthase 1(Sheep)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 32nMAssay Description:Reversible competitive inhibition of prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 110nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataKi:  130nMAssay Description:Binding affinity of compound towards prostaglandin G/H synthase 1 was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed