BDBM50072083 CHEMBL3407929

SMILES c1cc(c(cc1C(=O)[C@H]2C[C@@H]2C(=O)O)Cl)Cl

InChI Key InChIKey=ZBRKMOHDGFGXLN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072083   

TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50: 20nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50: 20nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50: 20nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50: 20nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed