BDBM50068267 (E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-phenyl)-propenone::3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one::CHEMBL141530::Echinatin

SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1

InChI Key InChIKey=QJKMIJNRNRLQSS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50068267   

LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Influenza A H9N2 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant activity expressed in HEK293T cells after 2 hrs by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of wild type H1N1 swine influenza virus neuraminidase activity expressed in HEK293T cells after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 3.03E+4nMAssay Description:Noncompetitive inhibition of Influenza A H1N1 virus neuraminidase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of Clostridium perfringens neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-FR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 5.77E+4nMAssay Description:Inhibition of cathepsin B (unknown origin) using RR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50068267(3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)p...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using 5'-FAM-AGGATCTAAAAGACTT-BHQ-3' as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed