BDBM50066650 1,3-BIS[[N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL]AMINO]-2-PROPANONE::CHEMBL281540::{(S)-1-[3-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-2-oxo-propylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester::{1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-2-oxo-propylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=APGQPPIXNOCMOK-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50066650   

TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  22nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  22nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  22nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  22nMAssay Description:Inhibitory activity measured against cathepsin K.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  340nMAssay Description:Inhibitory activity against Human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  890nMAssay Description:Inhibitory activity against Human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity against Human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPapain(Papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi: >1.00E+4nMAssay Description:The apparent binding affinity against PapainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetPapain(Papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50066650({1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyl...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity measured against papain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed