BDBM50066269 CHEMBL3401541

SMILES CC(C)N(C[C@@H]1CNC[C@H]1NS(=O)(=O)Cc2ccccc2)C(=O)c3ccc(c(c3)OCCCOC)OC

InChI Key InChIKey=WPSURGXSNWIBBJ-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50066269   

TargetCytochrome P450 2C9(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assay in presence of plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using DBF fluorometric substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066269(CHEMBL3401541)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam fluorometric substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed