BDBM50065456 CHEMBL3402741

SMILES CCN(CC)CCCOC(=O)Nc1cccc(c1)CN2C(=O)SCC(=N2)c3ccc(c(c3)OC)OC

InChI Key InChIKey=WVYHFPSGWCCXMO-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065456   

LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50: 400nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)