BDBM50055291 4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-yloxy)-butyric acid::CHEMBL356752

SMILES Cc1c(c2cc(ccc2n1Cc3ccccc3)OCCCC(=O)O)CC(=O)N

InChI Key InChIKey=STENXUCYNKOBHJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055291   

TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055291(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)
Affinity DataIC50: 152nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055291(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055291(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibitory activity against human pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)