BDBM50054486 CHEMBL141424::N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide

SMILES [H]/N=C(\N)/N1CCC[C@H](C1)C[C@@H](C=O)NC(=O)CN2CCC[C@@H](C2=O)NS(=O)(=O)Cc3ccccc3

InChI Key InChIKey=DATYERRDSFNBDN-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054486   

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 6.48E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 0.670nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)