BDBM50043918 CHEMBL3356044

SMILES COc1ccc(Cl)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1

InChI Key InChIKey=NQAKQMPWEPLRDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043918   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi R & D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043918BDBM50043918(CHEMBL3356044)
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi R & D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043918BDBM50043918(CHEMBL3356044)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi R & D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043918BDBM50043918(CHEMBL3356044)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi R & D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043918BDBM50043918(CHEMBL3356044)
Affinity DataIC50: 34nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed