BDBM50043803 (S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL291833::Cbz-L-Tyr

SMILES OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=MCRMUCXATQAAMN-UHFFFAOYSA-N

Data  2 KI  2 IC50  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043803   

TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043803(Cbz-L-Tyr | CHEMBL291833 | (S)-2-Benzyloxycarbonyl...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant full length stromelysin (FLS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043803(Cbz-L-Tyr | CHEMBL291833 | (S)-2-Benzyloxycarbonyl...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of recombinant stromelysin catalytic domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043803(Cbz-L-Tyr | CHEMBL291833 | (S)-2-Benzyloxycarbonyl...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of recombinant full length stromelysin (FLS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043803(Cbz-L-Tyr | CHEMBL291833 | (S)-2-Benzyloxycarbonyl...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of recombinant stromelysin catalytic domain (SCD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50043803   

HostPNGBDBM36126(gamma-cyclodextrin)
Japan Science and Technology Agency

GuestPNGBDBM50043803(Cbz-L-Tyr | CHEMBL291833 | (S)-2-Benzyloxycarbonyl...)
ITC DataΔG°: -3.11kcal/mole −TΔS°: 1.77kcal/mole ΔH°: -4.87kcal/mole logk: 192
pH: 6.9 T: 25.00°C