BDBM50037981 CHEMBL103102::CHEMBL216318::Piperidine-1-carboxamidine; compound with GENERIC INORGANIC NEUTRAL COMPONENT

SMILES [H]/N=C(\N)/N1CCCCC1

InChI Key InChIKey=QUUYRYYUKNNNNS-UHFFFAOYSA-N

Data  5 KI  2 Kd

PDB links: 14 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50037981   

TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKd:  1.07E+5nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKd:  1.97E+5nMAssay Description:Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:Inhibitory Activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:Inhibitory Activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  1.11E+5nMAssay Description:Binding affinity to thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)