BDBM50032592 CHEMBL3354169

SMILES CCN1C(=O)c2c(c(cs2)C#C)N=C1NC3CCCC3

InChI Key InChIKey=OANQHUSHGBNVCN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032592   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032592(CHEMBL3354169)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032592(CHEMBL3354169)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL