BDBM50030539 2-(2-Acetyl-5-methyl-phenylamino)-2-(2,6-dichloro-phenyl)-acetamide::CHEMBL37624::LOVIRIDE

SMILES Cc1ccc(c(c1)N[C@@H](c2c(cccc2Cl)Cl)C(=O)N)C(=O)C

InChI Key InChIKey=CJPLEFFCVDQQFZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030539   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Tosoh

Curated by ChEMBL
LigandPNGBDBM50030539(CHEMBL37624 | 2-(2-Acetyl-5-methyl-phenylamino)-2-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory effect on HIV-1 RT activity using template primer,poly (rA)-oligo (dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Tosoh

Curated by ChEMBL
LigandPNGBDBM50030539(CHEMBL37624 | 2-(2-Acetyl-5-methyl-phenylamino)-2-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory effect on HIV-1 RT activity using template primer,poly (rA)-oligo (dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50030539(CHEMBL37624 | 2-(2-Acetyl-5-methyl-phenylamino)-2-...)
Affinity DataEC50:  13nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)