BDBM50029216 (E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid phenethyl ester::3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid phenethyl ester::CHEMBL442022::phenethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate

SMILES COc1cc(ccc1O)/C=C/C(=O)OCCc2ccccc2

InChI Key InChIKey=CZQNYPBIOHVQQN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029216   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029216((E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid ph...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50029216((E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid ph...)
Affinity DataEC50:  7.90E+3nMAssay Description:Inhibition of TTR V30M mutant (unknown origin) expressed in Escherichia coli assessed as inhibition of amyloid fibril formation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029216((E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid ph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed