BDBM500286 US11021475, Example 16

SMILES CNC(=O)c1c(cc(nn1)Nc2ccccn2)Nc3ccccc3S(=O)(=O)C

InChI Key InChIKey=KUHISBZXQSKCLH-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500286   

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent

LigandBDBM500286(US11021475, Example 16)Copy SMILESCopy InChI

Affinity DataEC50:  6.57nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/29/2021
Entry Details
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PDB3D Structure (crystal)
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