BDBM50021437 5-Ethyl-5-phenylbarbituric acid::5-Phenyl-5-ethylbarbituric acid::5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione::5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL40::Phenobarbital::Phenobarbitol::Phenobarbitone::Phenobarbituric Acid::Phenylaethylbarbitursaeure::Phenylethylbarbiturate::Phenylethylbarbituric Acid::Phenylethylbarbitursaeure

SMILES CCC1(C(=O)NC(=O)NC1=O)c2ccccc2

InChI Key InChIKey=DDBREPKUVSBGFI-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021437   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 3.02E+6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 3.02E+6nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]BTX binding to guinea pig voltage-dependent sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Howard University

Curated by ChEMBL
LigandPNGBDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed