BDBM50018179 2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophene-6-carboxylic acid::CHEMBL22542::Imitrodast

SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1

InChI Key InChIKey=KRBSZXUPPSXPAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50018179   

TargetThromboxane-A synthase(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50: 13nMAssay Description:Inhibition of thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50: 13nMAssay Description:Inhibition of platelet microsomal thromboxane A2 synthetase in rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50: 6nMAssay Description:Inhibition of platelet microsomal thromboxane A synthetase in humansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed