BDBM50017897 CHEMBL3289023

SMILES [H]/N=C(\N)/c1ccc(cc1)Oc2cc(cc(c2)C(=O)NC3CCC(CC3)N)Oc4ccc(cc4)/C(=N/[H])/N

InChI Key InChIKey=PCTUHSSCHRLPLB-UHFFFAOYSA-N

Data  3 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50017897   

TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant matriptase (unknown origin) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hydrobromideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataKi:  516nMAssay Description:Inhibition of bovine plasma factor 10a using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50017897(CHEMBL3289023)
Affinity DataKi:  2.11E+3nMAssay Description:Inhibition of human thrombin using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hydrobromideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed