BDBM50011796 1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine(ET-18-OMe)::2-methoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate::CHEMBL28509::EDELFOSINE::Phosphoric acid 2-dimethylamino-ethyl ester 2-methoxy-3-octadecyloxy-propyl ester; ammonium::Phosphoric acid 2-trimethylamino-ethyl ester 2-methoxy-3-octadecyloxy-propyl ester::{2-[Hydroxy-(2-methoxy-3-octadecyloxy-propoxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium::{2-[Hydroxy-(2-methoxy-3-octadecyloxy-propoxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium(ET-18-OMe)

SMILES CCCCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OC

InChI Key InChIKey=MHFRGQHAERHWKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011796   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50011796(Phosphoric acid 2-trimethylamino-ethyl ester 2-met...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Akt phosphorylation in human insulin-stimulated A549 cells incubated for 2 hrs prior to insulin-induction measured after 30 mins by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50011796(Phosphoric acid 2-trimethylamino-ethyl ester 2-met...)
Affinity DataIC50: 1.80E+3nMT: 2°CAssay Description:PAF agonism was measured as the IC50 for aggregation of washed rabbit platelets after incubation for 30 min at 37 C.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50011796(Phosphoric acid 2-trimethylamino-ethyl ester 2-met...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Protein Kinase C (PKC) isolated from HL-60 human promyelocytic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details Article
PubMed