BDBM50008396 CHEMBL3235533

SMILES c1ccc(cc1)C(CC(=O)Nc2nc3ccccc3s2)c4ccccc4

InChI Key InChIKey=GYQWKTIZRYVFEM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008396   

TargetCasein kinase I isoform delta(Human)
Csic

Curated by ChEMBL
LigandPNGBDBM50008396(CHEMBL3235533)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetFrequenin 2, isoform D(Fruit fly)
Biological Research Center

Curated by ChEMBL
LigandPNGBDBM50008396(CHEMBL3235533)
Affinity DataKd:  1.13E+3nMAssay Description:Binding affinity to drosophila NCS1 expressed in Escherichia coli BL21 (DE3) by fluorescence emission assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal calcium sensor 1(Human)
Biological Research Center

Curated by ChEMBL
LigandPNGBDBM50008396(CHEMBL3235533)
Affinity DataKd:  1.25E+3nMAssay Description:Binding affinity to human NCS1 expressed in Escherichia coli BL21 Star (DE3) by fluorescence emission assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed