BDBM50002279 1-(4-Chloro-phenyl)-2-(1-cyclopropylmethyl-piperidin-4-yl)-ethanone; hydrobromide::CHEMBL544614

SMILES Clc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1

InChI Key InChIKey=LJRYGMQGFOOAQO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002279   

TargetSigma non-opioid intracellular receptor 1(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002279BDBM50002279(CHEMBL544614 | 1-(4-Chloro-phenyl)-2-(1-cyclopropy...)
Affinity DataKi:  8nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002279BDBM50002279(CHEMBL544614 | 1-(4-Chloro-phenyl)-2-(1-cyclopropy...)
Affinity DataKi:  495nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002279BDBM50002279(CHEMBL544614 | 1-(4-Chloro-phenyl)-2-(1-cyclopropy...)
Affinity DataIC50: 2.00E+3nMAssay Description:The compound was tested in vitro for its binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed