BDBM438227 US10618897, Example 80

SMILES COc1ccc2c(n1)C3(CCN(CC3)C(=O)c4ccc5c(c4)cn[nH]5)C(=O)N2CC(=O)N6CCC[C@H]6C(F)(F)F

InChI Key InChIKey=ZILKCBIBRQZYMB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438227   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent

LigandBDBM438227(US10618897, Example 80)Copy SMILESCopy InChI

Affinity DataIC50: 120nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/20/2020
Entry Details
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PDB3D Structure (crystal)
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