BDBM437773 US10597366, Compound 58

SMILES c1cc(c2c(c1C(F)(F)F)[C@@H](CC2)O)Oc3cc(cc(c3)F)F

InChI Key InChIKey=WYQNGHURDXWRST-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437773   

TargetEndothelial PAS domain-containing protein 1(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM437773(US10597366, Compound 58)
Affinity DataIC50: 5nMAssay Description:HIF-2a: The total assay volume was about 100 uL in the following configuration: 2 uL compound in 100% DMSO, 88 uL buffer with protein and probe and 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)