BDBM429286 APS-2-79::US10548897, Compound 21

SMILES Cc1cc(ccc1Nc2c3cc(c(cc3ncn2)OC)OC)Oc4ccccc4

InChI Key InChIKey=PEKZLFZZBGBOPJ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429286   

TargetKinase suppressor of Ras 2(Human)
Icahn School of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429286(APS-2-79 | US10548897, Compound 21)
Affinity DataIC50: 120nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
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Date in BDB:
11/7/2020
Entry Details
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PDB3D3D Structure (crystal)