BDBM427330 (S)-1-((6-(difluoromethyl)-2′-(fluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine::US10544120, Example 355::US10544120, Example 356

SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(CF)c1

InChI Key InChIKey=RIHPQFDTJBQUJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427330   

TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 427330BDBM427330(US10544120, Example 355 | (S)-1-((6-(difluoromethy...)
Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 427330BDBM427330(US10544120, Example 355 | (S)-1-((6-(difluoromethy...)
Affinity DataIC50: 82nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent