BDBM393276 5-(3,4- difluorobenzenesulfon- amidomethyl)-6- methyl-N-[(2-methyl- 1,3-thiazol-5- yl)methyl]pyrazine-2- carboxamide::US9963434, Table 12.219

SMILES Cc1c(ncc(n1)C(=O)NCc2cnc(s2)C)CNS(=O)(=O)c3ccc(c(c3)F)F

InChI Key InChIKey=GZXSPNTWOSSNMG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393276   

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Luc Therapeutics

US Patent

LigandBDBM393276(US9963434, Table 12.219 | 5-(3,4- difluorobenzenes...)Copy SMILESCopy InChI

Affinity DataIC50: 16.2nMAssay Description:Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/30/2020
Entry Details
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PDB3D Structure (crystal)
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