BDBM36359 (3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide::CID16202132::E7107

SMILES CC[C@@H]([C@@H](C)[C@@H]1[C@H](O1)C[C@](C)(/C=C/C=C(\C)/[C@@H]2[C@H](/C=C/[C@@H]([C@](CC[C@H](CC(=O)O2)O)(C)O)OC(=O)N3CCN(CC3)C4CCCCCC4)C)O)O

InChI Key InChIKey=MNOMBFWMICHMKG-UHFFFAOYSA-N

Data  2 EC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36359   

LigandPNGBDBM36359(CID16202132 | (3R,6R,7S,8E,10S,11S,12E,14E,16R,18R...)
Affinity DataEC50:  3.60nMpH: 7.8 T: 2°CAssay Description:Placental alkaline phosphatase (PLAP) reporter assay controlled by VEGF promoter (VEGF-PLAP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM36359(CID16202132 | (3R,6R,7S,8E,10S,11S,12E,14E,16R,18R...)
Affinity DataEC50:  3.20nMpH: 7.8 T: 2°CAssay Description:Cell proliferation assay using WiDrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)