BDBM35540 4-hydroxy-2H-chromen-2-one core, 16

SMILES Cc1cc2c(cc1C)OC(=O)C(=C2O)Cc3cccc4c3cccc4

InChI Key InChIKey=CLIXIKBUGAHFJT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35540   

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35540(4-hydroxy-2H-chromen-2-one core, 16)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35540(4-hydroxy-2H-chromen-2-one core, 16)
Affinity DataIC50: 7.70nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)