BDBM35051 benzothienopyrimidinone deriv., 3b

SMILES c1cc(c2c(c1Cl)c3c(s2)C(=O)NC=N3)Cl

InChI Key InChIKey=DJUSDFVEBBYFFL-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 35051   

TargetSerine/threonine-protein kinase pim-3(Human)
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  11nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  130nM ΔG°:  -9.39kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  164nM ΔG°:  -9.25kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed