BDBM34988 benzothienopyrimidinone deriv., 6e

SMILES O[C@H]1CCN(Cc2nc3c4cc(Cl)ccc4sc3c(=O)[nH]2)C1

InChI Key InChIKey=DSUSQUXNJRQJMI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34988   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM34988(benzothienopyrimidinone deriv., 6e)
Affinity DataKi:  5nM ΔG°:  -11.2kcal/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM34988(benzothienopyrimidinone deriv., 6e)
Affinity DataKi:  29nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed