BDBM34071 benzamide derivative, 6

SMILES Cn1ccnc1Sc2cc(c(cc2F)N)C(=O)Nc3nccs3

InChI Key InChIKey=YUCYMQBDBXVNCE-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34071   

TargetGlycogen phosphorylase, muscle form(Rabbit)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataIC50: 4.39E+4nMpH: 7.2 T: 2°CAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataEC50:  67.1nMAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataKd:  360nMAssay Description:Binding affinity to human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluorometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)