BDBM333906 (S)-(3-((8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-methyl-9H- purin-6-yl)oxy)pyrrolidin-1- yl)(tetrahydro-2H-pyran-4- yl)methanone::US9730940, Compound 2-8

SMILES CCn1ncc(c1C)-c1nc2c(OC3CCN(C3)C(=O)C3CCOCC3)ncnc2n1C

InChI Key InChIKey=FHKPLLOSJHHKNU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333906   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM333906((S)-(3-((8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-m...)Copy SMILESCopy InChI

Affinity DataIC50: 4.30nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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