BDBM32460 piperazine amide, 4g

SMILES C#CCN1CCN(CC1)c2c(cccc2Cl)NC(=O)c3ccc(o3)Br

InChI Key InChIKey=MEFJFXHHHNDHEN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32460   

LigandPNGBDBM32460(piperazine amide, 4g)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM32460(piperazine amide, 4g)
Affinity DataIC50: 140nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)