BDBM31637 tetrahydrobenzothiophene (THBT), 6

SMILES C[C@H]1CCc2c(sc(c2C(=O)N)NC(=O)c3ccccc3[N+](=O)[O-])C1

InChI Key InChIKey=OBHKTNMETRQPKN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31637   

LigandPNGBDBM31637(tetrahydrobenzothiophene (THBT), 6)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31637(tetrahydrobenzothiophene (THBT), 6)
Affinity DataIC50: 501nMpH: 7.5 T: 2°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed