BDBM302542 N5-(tert-Butyl)-2-(3-chloro-4- fluorophenyl)-6,7- dihydropyrazolo[1,5-a]pyrazine- 3,5(4H)-dicarboxamide::US9598423, Example 108

SMILES CC(C)(C)NC(=O)N1CCn2nc(c(C(N)=O)c2C1)-c1ccc(F)c(Cl)c1

InChI Key InChIKey=PJIBAKKGFKDBLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302542   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302542(N5-(tert-Butyl)-2-(3-chloro-4- fluorophenyl)-6,7- ...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302542(N5-(tert-Butyl)-2-(3-chloro-4- fluorophenyl)-6,7- ...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent