BDBM26998 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide::TRICHLORMETHIAZIDE::trichloromethiazide, 6

SMILES c1c2c(cc(c1Cl)S(=O)(=O)N)S(=O)(=O)N[C@@H](N2)C(Cl)Cl

InChI Key InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 26998   

TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  7.90nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  87nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  91nM ΔG°:  -9.44kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  134nM ΔG°:  -9.21kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  312nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  345nM ΔG°:  -8.66kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  449nM ΔG°:  -8.51kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  645nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  763nM ΔG°:  -8.20kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  2.46E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  3.45E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(trichloromethiazide, 6 | 6-chloro-3-(dichloromethy...)
Affinity DataKi:  5.60E+5nM ΔG°:  -4.36kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed