BDBM26996 CHEMBL21485::PhB(OH)2::Phenyl-boronic acid::Phenylboronic acid, 22::benzeneboronic acid::phenylboranediol::phenylboronic acid
SMILES B(c1ccccc1)(O)O
InChI Key InChIKey=HXITXNWTGFUOAU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 99 hits for monomerid = 26996
Affinity DataIC50: 1.48E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
TargetSuccinyl-diaminopimelate desuccinylase(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Loyola University
Curated by ChEMBL
Loyola University
Curated by ChEMBL
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of Haemophilus influenzae recombinant DapEMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition constant against ChymotrypsinogenMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universita Degli Studi Di Firenze
Universita Degli Studi Di Firenze
Affinity DataKi: 7.00E+3nM ΔG°: -6.91kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Florida
Curated by ChEMBL
University of Florida
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMpH: 8.3Assay Description:Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for...More data for this Ligand-Target Pair
Affinity DataKi: 8.10E+3nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.60E+3nMAssay Description:Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School
Curated by ChEMBL
Northwestern University Medical School
Curated by ChEMBL
Affinity DataKi: 1.05E+4nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of mouse CA15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA13 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetSuccinyl-diaminopimelate desuccinylase(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Loyola University
Curated by ChEMBL
Loyola University
Curated by ChEMBL
Affinity DataKi: 5.69E+4nMAssay Description:Inhibition of Haemophilus influenzae recombinant DapE by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.78E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 7.30E+4nM ΔG°: -5.64kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 8.10E+4nM ΔG°: -5.48kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
Affinity DataKi: 8.50E+4nM ΔG°: -5.46kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20E+4nMAssay Description:Inhibition of human recombinant full length CA14More data for this Ligand-Target Pair
Affinity DataKi: 9.60E+4nMAssay Description:Competitive inhibition of Subtilisin BL M222S-mutated enzyme from Bacillus lentusMore data for this Ligand-Target Pair
Affinity DataKi: 9.70E+4nM ΔG°: -5.38kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.70E+4nM ΔG°: -5.47kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 5.86E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 5.86E+7nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 2.85E+6nMAssay Description:Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10More data for this Ligand-Target Pair
Affinity DataKi: 5.86E+7nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+5nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+7nMAssay Description:Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.86E+7nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition of Candida glabrata carbonic anhydrase by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 2.30E+5nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+5nMAssay Description:Competitive inhibition of Subtilisin BL wild type enzyme from Bacillus lentusMore data for this Ligand-Target Pair