BDBM26131 4-(dihydroxyboranyl)benzonitrile::Phenylboronic Acid, 10

SMILES OB(O)c1ccc(cc1)C#N

InChI Key InChIKey=CEBAHYWORUOILU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26131   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Oxford

LigandPNGBDBM26131(4-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Oxford

LigandPNGBDBM26131(4-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26131(4-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutoinducer 2 sensor kinase/phosphatase LuxQ(Vibrio harveyi)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM26131(4-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity against LuxPQ quorum sensing system in Vibrio harveyi MM32 assessed as inhibition of luminescence intensity incubated for 3 to 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed