BDBM25425 2-(2,4-dichlorophenoxy)-5-(pyridin-2-ylmethyl)phenol::Triclosan derivative, 26

SMILES c1ccnc(c1)Cc2ccc(c(c2)O)Oc3ccc(cc3Cl)Cl

InChI Key InChIKey=AOVDSWPGWPRTSR-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25425   

TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM25425(2-(2,4-dichlorophenoxy)-5-(pyridin-2-ylmethyl)phen...)
Affinity DataIC50: 640nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-acyl-carrier protein reductase(malaria parasite P. falciparum)
International Centre For Science and High Technology

Curated by ChEMBL
LigandPNGBDBM25425(2-(2,4-dichlorophenoxy)-5-(pyridin-2-ylmethyl)phen...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Plasmodium falciparum enoyl-acyl carrier protein reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)