BDBM253042 US9493447, 1001

SMILES CCOC(C(=O)c1ccc(o1)-c1cc(OC)c(Cl)c(OC)c1)c1ccc(cc1)-c1nnc(C)s1

InChI Key InChIKey=QQHJRLKSCSRMEM-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 253042   

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 545nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 5.74E+3nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 0.620nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM253042(US9493447, 1001)
Affinity DataIC50: 0.620nMpH: 7.5 T: 2°CAssay Description:The PDE assay medium consisted of (final concentrations); 50 mM Tris-HCL, pH 7.5; 8.3 mM MgCl2; 1.7 mM EGTA; 0.5 mg/mL bovine serum albumin; and subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent