BDBM25257 ({hydroxy[(3-methylbut-3-en-1-yl)oxy]phosphoryl}oxy)phosphonic acid::[14C]IPP::[14C]isopentenyl diphosphate

SMILES CC(=C)CCO[P@@](=O)(O)OP(=O)(O)O

InChI Key InChIKey=NUHSROFQTUXZQQ-UHFFFAOYSA-N

Data  1 IC50  3 EC50

PDB links: 70 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25257   

TargetButyrophilin subfamily 3 member A1(Human)
Western Michigan University

Curated by ChEMBL
LigandPNGBDBM25257([14C]isopentenyl diphosphate | ({hydroxy[(3-methyl...)
Affinity DataEC50:  7.10E+4nMAssay Description:Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated IFNgamma production measured after 48 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetButyrophilin subfamily 3 member A1(Human)
Western Michigan University

Curated by ChEMBL
LigandPNGBDBM25257([14C]isopentenyl diphosphate | ({hydroxy[(3-methyl...)
Affinity DataIC50: 5.13E+5nMAssay Description:Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 B30.2 domain (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetButyrophilin subfamily 3 member A1(Human)
Western Michigan University

Curated by ChEMBL
LigandPNGBDBM25257([14C]isopentenyl diphosphate | ({hydroxy[(3-methyl...)
Affinity DataEC50:  3.60E+4nMAssay Description:Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated cell proliferation by measuring increase i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetButyrophilin subfamily 3 member A1(Human)
Western Michigan University

Curated by ChEMBL
LigandPNGBDBM25257([14C]isopentenyl diphosphate | ({hydroxy[(3-methyl...)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)